Cell death: Shadow Baxing

Cell death: Shadow Baxing

Bcl-2, one of a family of key regulators of apoptosis, was the first cell-death machinery component to be identified, but how the family functions is still not clear. Mammalian Bax, a pro-apoptotic family member, can cause yeast cells to die, and two recent yeast genetic screens shed light on how Bax might function.

Valuing Life under the Shadow of Death

This paper proposes an axiomatic formulation of preferences that rank lotteries involving lives of different lengths. Our axioms formalize two fundamental assumptions: preferences fulfill standard axioms of expected utility theory and are stationary. They lead to a class of utility functions that is much larger than the set of additive utility functions. We discuss the theoretical properties of...

The vitamin A story--lifting the shadow of death. Preface.

Ovarian Basaloid Carcinoma with Shadow Cell Differentiation

So-called shadow cell differentiation (SCD) is typical for pilomatrixoma and other skin lesions with follicular differentiation, but it was rarely described also in some visceral carcinomas. We report a case of ovarian basaloid carcinoma with SCD. The tumor presented as a 14 cm ovarian mass in a 45-year-old woman, and therefore the adnexectomy and hysterectomy were performed. The tumor was of h...

Different cell death types determination in juvenile mice ovarian follicles

Follicular atresia is a phenomenon that leads to evacuation of the ovary from the oocytes and the occurrence of menopause. The contribution of various types of cell death in atresia at different follicular developmental stages requires extensive investigation. In this study, we evaluated 3 types of programmed </...